Techniques in Gastrointestinal Endoscopy
Volume 7, Issue 2 , Pages 60-65 , April 2005

Photodynamic Therapy for High-Grade Dysplasia in Barrett’s Esophagus

  • Hugh Barr, MD, ChM (FRCS, FRCSEd)

      Affiliations

    • Corresponding Author InformationAddress reprint requests to Professor Hugh Barr, MD, ChM, FRCS, FRCSE, Cranfield Postgraduate Medical School, Gloucestershire Royal Hospital, Great Western Road, Gloucester, GL1 3NN, United Kingdom.

References 

  1. Kasting JF . The rise of atmospheric oxygen . Science . 2001;293:819–820
  2. Barr H , Kendall C , Reyes-Goddard J , et al.   Clinical aspects of photodynamic therapy . Sci Prog . 2002;85:131–150
  3. Moreira D , Le Guyader H , Phillippe H . The origin of red algae and the evolution of chloroplasts . Nature . 2000;405:69–72
  4. Barr H , Dix AJ , Kendall C , et al.   The potential for photodynamic therapy in the management of Upper Gastrointestinal Disease . Aliment Pharmacol Ther . 2001;15:311–321
  5. McCaughan JS , Hicks W , Laufman L , et al.   Palliation of esophageal malignancy with photoradiation therapy . Cancer . 1984;54:2905–2910
  6. Schlemper RJ , Riddell RH , Kato Y , et al.   The Vienna classification of gastrointestinal epithelial neoplasia . Gut . 2000;47:251–255
  7. Montgomery E , Bronner MP , Goldblum JR , et al.   Reproducibility of the diagnosis of dysplasia in Barrett’s oesophagus (a reaffirmation) . Hum Path . 2001;32:268–378
  8. Ormsby AH , Petras RE , Henricks  , et al.   Observer variation in the diagnosis of superficial oesophageal adenocarcinoma . Gut . 2002;51:671–676
  9. Barr H , Fitzgerald RC . Ablative mucosectomy is the procedure of choice to prevent Barrett’s cancer . Gut . 2003;52:14–17
  10. Schnell TG , Sontag SJ , Chejfec G , et al.   Long term non-surgical management of Barrett’s esophagus with hig-grade dysplasia . Gastroenterology . 2001;120:1607–1619
  11. Kara MA , Bergman JJ , Tytgat GNJ . Follow-up for high-grade dysplasia in Barrett’s oesophagus . Gastrointest Endosc Clin N Am . 2003;13:513–533
  12. Collard JM . High-grade dysplasia in Barrett’s esophagus. The case for oesophagectomy . Chest Surg Clin N Am . 2002;12:77–92
  13. Montgomery E , Goldblum JR , Greenson JK , et al.   Dysplasia as a predictive marker for invasive carcinoma in Barrett esophagus (a follow-up study based on 138 cases from diagnostic variability study) . Hum Path . 2001;32:379–388
  14. Ouata-Lascar R , Fitzgerald RC , Triadafilopoulos G . Differentiation and proliferation in Barrett’s esophagus and the effects of acid suppression . Gastroenterology . 1999;117:327–335
  15. Hameeteman W , Tytgat GN , Houthoff HF , et al.   Barrett’s oesophagus (development and adenocarcinoma) . Gastroenterology . 1989;96:1249–1256
  16. Bailey T , Biddlestone L , Sheherd N , et al.   Altered Cadherin and Catenin Complex’s in the Barrett’s esophagus-dysplasia-adenocarcinoma sequence (correlation with dedifferentiation and epithelial-mesenchymal transition) . Am J Pathol . 1998;152:1–10
  17. Ackroyd R , Brown NJ , Stephenson TJ , et al.   Ablation treatment for Barrett oesophagus (what depth of tissue destruction is needed) . J Clin Pathol . 1999;52:509–512
  18. Coad RA , Warner PJ , Barr H , et al.   On the genesis of Barrett’s oesophagus (a three dimensional study of the relationship between oesophageal gland ducts, Barrett’s oesophagus and associated squamous islands) . Br J Cancer . 2004;91:P105; (abstr)
  19. Barr H . Barrett’s esophagus (treatment with 5-aminolevulinic acid photodynamic therapy) . Gastrointest Endosc Clin N Am . 2000;10:421–438
  20. Stone N . Standardizing Dosimetry in esophageal PDT (an argument for use of centering devices and removal of misleading units) . Technol Cancer Res Treat . 2003;2:76–84
  21. Gossner L , Stolte M , Stroke R , et al.   Photodynamic therapy of high-grade dysplasia and early stage carcinomas by means of 5-aminolaevulinic acid . Gastroenterology . 1998;114:447–455
  22. Barr H , Tan WC , Shepherd NA . Photodynamic therapy (PDT) using 5-aminolaevulinic acid (5-ALA) for oesophageal adenocarcinoma associated with Barrett’s metaplasia . Lasers Med Sci . 1997;4:3; (abstr 21)
  23. Barr H , Shepherd NA , Dix A , et al.   Eradication of high grade dysplasia in columnar-lined (Barrett‘s) oesophagus using photodynamic therapy with endogenously generated protoporphyrin IX . Lancet . 1996;348:584–585
  24. Tan WC , Fulljames C , Stone N , et al.   Photodynamic therapy using 5-aminolaevulinic acid for oesophageal adenocarcinoma associated with Barrett’s metaplasia . J Photochem Photobiol B Biol . 1999;53:75–80
  25. Biddlestone LR , Barham CP , Wilkinson SP , et al.   The histopathology of treated Barrett’s esophagus . Am J Surg Pathol . 1998;22:239–245
  26. Ackroyd R , Brown NJ , Davis MF , et al.   Photodynamic therapy for dysplastic Barrett’s oesophagus (a prospective, double blind, randomised, placebo-controlled trial) . Gut . 2000;47:613–617
  27. Krishnadath K , Wang KK , Liu W , et al.   Persistent genetic abnormalities in Barrett’s esophagus after photodynamic therapy . Gastroenterology . 2000;119:624–630
  28. Overholt BF , Panjehpour M , Halberg DL . Photodynamic therapy of Barrett’s oesophagus with dysplasia and/or early stage carcinoma (long-term results) . Gastrointest Endosc . 2003;58:193–198
  29. Sibille A , Lambert R , Souquet J-C , et al.   Long-term survival after photodynamic therapy for esophageal cancer . Gastroenterology . 1995;108:337–344
  30. Patrice T , Foultier MT , Yactayo S , et al.   Endoscopic photodynamic therapy with hematoporphyrin Derivative for primary treatment of gastrointestinal neoplasms in inoperable patients . Dig Dis Sci . 1990;35:545–552
  31. Corti L , Skarlatos J , Boso C , et al.   Outcome of patients receiving photodynamic therapy for early esophageal cancer . Int J Radiat Oncol Biol Phys . 2000;47:419–424
  32. Gossner L , May A , Pech O , et al.   Photodynamic therapy of Barrett’s esopagus with dysplasia or early cancer . Gastroenterology . 1999;116: (abstr G1811)
  33. Javaid B , Watt P , Krasner N . Photodynamic therapy (PDT) for oesophageal dysplasia and early carcinoma with mTHPC (m-tetrahydroxyphenyl chlorin) (a preliminary study) . Lasers Med Sci . 2002;17:51–56
  34. Ragunath K , Krasner N , Raman VS , et al.   Endoscopic ablation of dysplastic barrett’s oesophagus comparing Argon Plasma Coagulation and Photodynamic therapy (short term results of a randomized prospective trial) . Lasers Med Sci . 2005; (in press)
  35. Hage M , Sieresma PD , van Dekken H , et al.   5-Aminolevulinic acid photodynamic therapy versus argon plasma coagulation for ablation of Barrett’s oesophagus (a randomised trial) . Gut . 2004;53:785–790
  36. Kelty CJ , Ackroyd R , Brown NJ . Endoscopic ablation of Barrett’s oesophagus (a randomised controlled trial of photodynamic therapy vs argon plasma coagulation) . Br J Sci . 2004;91: (abstr 42)
  37. Overholt BF , Lightdale CJ , Wang K , et al.   International Multicenter Partially Blinded Randomised Study of the efficacy of photodynamic therapy (PDT) using Porfimer Sodium (POR) for the ablation of high-grade dysplasia (HGD) in Barrett’s esophagus (BE) (results of 24 month follow-up) . Gastroenterology . 2003;124: (abstr A20)

PII: S1096-2883(05)00003-3

doi: 10.1016/j.tgie.2005.02.002

Techniques in Gastrointestinal Endoscopy
Volume 7, Issue 2 , Pages 60-65 , April 2005

Article Tools

* Image Usage & Resolution