Techniques in Gastrointestinal Endoscopy
Volume 11, Issue 1 , Pages 19-25 , January 2009

Endoscopic methods for the diagnosis of chronic pancreatitis

  • Daniel K. Mullady, MD

      Affiliations

    • Corresponding Author InformationAddress reprint requests to Daniel K. Mullady, MD, Washington University School of Medicine, Campus Box 8124, 660 S. Euclid Ave., St. Louis, MO
  • ,
  • Dayna Early, MD

References 

  1. Banks PA. Classification and diagnosis of chronic pancreatitis. J Gastroenterol. 2007;42(suppl XVII):148–151
  2. Masci E, Toti G, Mariani A, et al. Complications of diagnostic and therapeutic ERCP: a prospective multicenter study. Am J Gastroenterol. 2001;96:417-2
  3. Christensen M, Matzen P, Schulze S, et al. Complications of ERCP: a prospective study. Gastrointest Endosc. 2004;60:721–731
  4. Cheng CL, Sherman S, Watkins JL, et al. Risk factors for post ERCP pancreatitis: a prospective multicenter study. Am J Gastroenterol. 2006;101:139–147
  5. Sarner M, Cotton PB. Classification of chronic pancreatitis. Gut. 1984;25:756–759
  6. Axon AT, Classen M, Cotton PB, et al. Pancreatography in chronic pancreatitis: international definitions. Gut. 1984;25:1107–1112
  7. Anand BS, Vij JC, Mac HS, et al. Effect of aging on the pancreatic ducts: a study based on endoscopic retrograde pancreatography. Gastrointest Endosc. 1989;35:210–213
  8. Hastier P, Buckley MJ, Dumas R, et al. A study of the effect of age on pancreatic duct morphology. Gastrointest Endosc. 1998;8:53–57
  9. Hastier P, Buckley MJ, Francois E, et al. A prospective study of pancreatic disease in patients with alcoholic cirrhosis: comparative diagnostic value of ERCP and EUS and long-term significance of isolated parenchymal abnormalities. Gastrointest Endosc. 1999;49:705–709
  10. Kochhar R, Sethy PK, Sood A, et al. Concurrent pancreatic ductal changes in alcoholic liver disease. J Gastroenterol Hepatol. 2003;18:1067–1070
  11. Tamura R, Ishibashi T, Takahashi S. Chronic pancreatitis: MRCP versus ERCP for quantitative caliber measurement and qualitative evaluation. Radiology. 2006;238:920–927
  12. Stevens T, Conwell DL, Zuccaro G, et al. Comparison of endoscopic ultrasound and endoscopic retrograde pancreatography for the prediction of pancreatic exocrine insufficiency. Dig Dis Sci. 2008;53:1146–1151
  13. DeWitt J, McGreevy K, LeBlanc J, et al. EUS-guided Trucut biopsy of suspected nonfocal chronic pancreatitis. Gastrointest Endosc. 2005;62:76–84
  14. Zimmerman MJ, Mishra G, Lewin DN. Comparison of EUS findings with histopathology in chronic pancreatitis. Gastrointest Endosc. 1997;45:AB185
  15. Raimondo M, Wallace MB. Diagnosis of early chronic pancreatitis by endoscopic ultrasound (Are we there yet?). JOP. 2004;5:1–7
  16. Walsh T, Rode J, Theis B, et al. Minimal change chronic pancreatitis. Gut. 1992;33:1566–1571
  17. Hollerbach S, Klamann A, Topalidis T, et al. Endoscopic ultrasonography (EUS) and fine-needle aspiration (FNA) cytology for diagnosis of chronic pancreatitis. Endoscopy. 2001;33:824–831
  18. Irisawa A, Katakura K, Ohira H, et al. Usefulness of endoscopic ultrasound to diagnose the severity of chronic pancreatitis. J Gastroenterol. 2007;42(suppl 17):90–94
  19. Brand B, Pfaff T, Bimoeller K, et al. Endoscopic ultrasound for differential diagnosis of focal pancreatic lesions, confirmed by surgery. Scand J Gastroenterol. 2000;35:1221–1228
  20. Varadarajulu S, Tamhane A, Eloubeidi M. Yield of EUS-guided FNA of pancreatic masses in the presence or the absence of chronic pancreatitis. Gastrointest Endosc. 2005;62:728–736
  21. Dreiling DA. Pancreatic secretory testing in 1974. Gut. 1975;16:53–57
  22. Conwell DL, Zuccaro G, Vargo J, et al. An endoscopic pancreatic function test with synthetic porcine secretin for the evaluation of chronic abdominal pain and suspected chronic pancreatitis. Gastrointest Endosc. 2003;57:37–40
  23. Stevens T, Conwell DL, Zuccaro G, et al. Stability of bicarbonate concentration in duodenal fluid measured by laboratory auto-analyzer [abstract]. Pancreas. 2004;29:A342
  24. Conwell DL, Zuccaro G, Vargo JJ, et al. Comparison of the secretin stimulated endoscopic pancreatic function test to retrograde pancreatogram. Dig Dis Sci. 2007;52:1076–1081
  25. Stevens T, Conwell DL, Zuccaro G, et al. A randomized crossover study of secretin-stimulated endoscopic and Dreiling tube pancreatic function test methods in healthy subjects. Am J Gastroenterol. 2006;101:351–355
  26. Conwell DL, Zuccaro G, Purich E, et al. The effect of moderate sedation on exocrine pancreas function in normal healthy subjects: a prospective, randomized, cross-over trial using the synthetic porcine secretin stimulated endoscopic pancreatic function test (ePFT). Am J Gastroenterol. 2005;100:1161–1166
  27. Stevens T, Conwell DL, Zuccaro G, et al. A prospective cross-over study comparing secretin-stimulated endoscopic and Dreiling tube pancreatic function testing in patients evaluated for chronic pancreatitis. Gastrointest Endosc. 2008;67:458–466
  28. Draganov P, George S, Toskes PP, et al. Is a 15-minute collection of duodenal secretions after secretin stimulation sufficient to diagnose chronic pancreatitis?. Pancreas. 2004;28:89–92
  29. Moolsintong P, Burton FR. Pancreatic function testing is best determined by the extended endoscopic collection technique. Pancreas. 2008;37:418–421
  30. Stevens T, Conwell DL, Zuccaro G, et al. The efficiency of endoscopic pancreatic function testing is optimized using duodenal aspirates at 30 and 45 minutes after intravenous secretin. Am J Gastro. 2007;102:297–301
  31. Alkaade S, Cem Balci N, Momtahen AJ, et al. Normal pancreatic exocrine function does not exclude MRI/MRCP chronic pancreatitis findings. J Clin Gastroenterol. 2008;42:950–955
  32. Micames CG, Gress FG. EUS elastography: a step ahead. Gastrointest Endosc. 2007;65:979–981
  33. Janssen J, Schlorer E, Greiner L. EUS elastography of the pancreas: feasibility and pattern description of the normal pancreas, chronic pancreatitis, and focal pancreatic lesions. Gastrointest Endosc. 2007;65:971–978
  34. Das A, Nguyen C, Li F, et al. Digital image analysis of EUS images accurately differentiates pancreatic cancer from chronic pancreatitis and normal tissue. Gastrointest Endosc. 2008;67:61–67

 The author has no direct financial interests that might pose a conflict of interest in connection with the submitted manuscript.

PII: S1096-2883(09)00004-7

doi: 10.1016/j.tgie.2009.02.002

Techniques in Gastrointestinal Endoscopy
Volume 11, Issue 1 , Pages 19-25 , January 2009