Techniques in Gastrointestinal Endoscopy
Volume 12, Issue 1 , Pages 53-60, January 2010

Endoscopic ampullectomy

  • Nam Q. Nguyen, MBBS, PhD
  • ,
  • Kenneth F. Binmoeller, MD

      Affiliations

    • Corresponding Author InformationAddress reprint requests to Kenneth F. Binmoeller, MD, Interventional Endoscopy Services, California Pacific Medical Center, San Francisco, CA 94115

Interventional Endoscopy Services, California Pacific Medical Center, San Francisco, California

Ampullary tumors are rare tumors of the gastrointestinal tract. Compared with surgery, the endoscopic approach to remove these tumors by ampullectomy is associated with lower morbidity and mortality. Recent developments in endoscopic ultrasound, including intraductal ultrasound, have enabled accurate T staging of these tumors, and allowed the selection of appropriate candidates for endoscopic therapy. Currently, there is no standardization for the technique of endoscopic ampullectomy. In expert hands, endoscopic ampullectomy for benign adenomas leads to successful tumor eradication in more than 85% of patients. Regular endoscopic surveillance of the resected site is essential in all patients after ampullectomy, as tumor recurrence occurs in up to 20% of patients. This article reviews and discusses the indications for, and techniques and outcomes of, endoscopic ampullectomy.

Keywords: Ampulla of Vater, Ampullectomy, Papillectomy, Ampulla resection

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 The authors report no direct financial interests that might pose a conflict of interest in connection with the submitted manuscript.

PII: S1096-2883(10)00006-9

doi:10.1016/j.tgie.2010.01.005

Techniques in Gastrointestinal Endoscopy
Volume 12, Issue 1 , Pages 53-60, January 2010